Lymphedema
Lymphedema is an abnormal accumulation of protein-rich fluid in the interstitial
space. This not only can cause swelling, but can also result in changes to the
skin, infection, and decreased wound healing where wounds are present.
Causes
Lymphedema involves an impairment of the lymphatic system,
resulting in decreased ability to remove fluid from the tissues.
There are two main classes of Lymphedema - Primary and Secondary.
Primary lymphedema in
some instances is congenital or often arises later in life.
Secondary lymphedema arises as the result of damage to components the lymphatic
system, (i.e. radiation, surgery, trauma, or infection).
Symptoms
The primary clinical presentation of lymphedema is swelling, caused by the accumulation of
fluid and protein in the interstitial space.
As lymphedema progresses, the skin can become fibrotic and darkened. This is due to
the accumulation of proteins and other elements that would normally be removed
by the lymphatic system.
With lymphedema, there is an increased risk of infection because protein rich
fluid accumulation creates an environment favorable to bacterial growth.
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